Package: TrialEmulation
Title: Causal Analysis of Observational Time-to-Event Data
Version: 0.0.4.11
Authors@R: c(
    person("Isaac", "Gravestock", , "isaac.gravestock@roche.com", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0003-0283-2065")),
    person("Li", "Su", , "li.su@mrc-bsu.cam.ac.uk", role = "aut"),
    person("Roonak", "Rezvani", , "roonak.r74@gmail.com", role = "aut",
           comment = c(ORCID = "0000-0001-5580-5058", "Original package author")),
    person("Julia", "Moesch", , "julia.moesch@roche.com", role = "aut"),
    person("Medical Research Council (MRC)", role = "fnd"),
    person("F. Hoffmann-La Roche AG", role = c("cph", "fnd"))
  )
Description: Implements target trial emulation methods to apply
        randomized clinical trial design and analysis in an
        observational setting. Using marginal structural models, it can
        estimate intention-to-treat and per-protocol effects in
        emulated trials using electronic health records. A description
        and application of the method can be found in Danaei et al
        (2013) <doi:10.1177/0962280211403603>.
License: Apache License (>= 2)
URL: https://causal-lda.github.io/TrialEmulation/,
        https://github.com/Causal-LDA/TrialEmulation
BugReports: https://github.com/Causal-LDA/TrialEmulation/issues
Depends: R (>= 4.1.0)
Imports: broom (>= 0.7.10), checkmate, data.table (>= 1.9.8), DBI,
        duckdb, formula.tools, lifecycle, lmtest, methods, mvtnorm,
        Rcpp, sandwich, future.apply
Suggests: knitr, parsnip, rmarkdown, rpart, testthat (>= 3.0.0), withr
LinkingTo: Rcpp
VignetteBuilder: knitr
Config/testthat/edition: 3
Encoding: UTF-8
Language: en-GB
LazyData: true
LazyDataCompression: xz
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Collate: 'RcppExports.R' 'bootstrap.R' 'bootstrap_helpers.R'
        'calculate_weights.R' 'data.R' 'data_extension.R'
        'data_manipulation.R' 'data_preparation.R' 'data_simulation.R'
        'data_utils.R' 'expand_trials.R' 'generics.R' 'initiators.R'
        'lr_utils.R' 'te_model_fitter.R' 'te_outcome_model.R'
        'te_datastore.R' 'te_weights.R' 'te_data.R' 'te_expansion.R'
        'trial_sequence.R' 'modelling.R' 'package.R' 'predict.R'
        'robust.R' 'sampling.R' 'te_datastore_csv.R'
        'te_datastore_duckdb.R' 'te_parsnip.R' 'te_stats_glm_logit.R'
        'utils.R' 'weighting.R'
Config/pak/sysreqs: libicu-dev xz-utils
Repository: https://causal-lda.r-universe.dev
Date/Publication: 2026-04-27 15:15:23 UTC
RemoteUrl: https://github.com/causal-lda/trialemulation
RemoteRef: HEAD
RemoteSha: 6964cf73eeb5c344f56496754b8dc86da86bc6e9
NeedsCompilation: yes
Packaged: 2026-05-27 06:25:59 UTC; root
Author: Isaac Gravestock [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-0283-2065>),
  Li Su [aut],
  Roonak Rezvani [aut] (ORCID: <https://orcid.org/0000-0001-5580-5058>,
    Original package author),
  Julia Moesch [aut],
  Medical Research Council (MRC) [fnd],
  F. Hoffmann-La Roche AG [cph, fnd]
Maintainer: Isaac Gravestock <isaac.gravestock@roche.com>